GHK-Cu Topical Powder Research Compound
Topical Powder Format • ≥99% HPLC Purity • Ships in 1–2 Business Days • U.S. Warehouses
GHK-Cu Topical Powder (Glycyl-L-Histidyl-L-Lysine Copper, CAS 49557-75-7) is a naturally occurring copper-binding tripeptide supplied by Nextday Peptides in a high-fill powder format for laboratory formulation research and analytical applications. Unlike the standard reconstitutable vial format, this topical powder variant is supplied in larger quantities suited for researchers investigating dermal penetration models, formulation development studies, and skin biology research applications. Each batch is independently verified to ≥99% HPLC purity with a Certificate of Analysis available on request. For scientific research use only.
Compound Specifications
| Compound Name | GHK-Cu Topical Powder / Glycyl-L-Histidyl-L-Lysine Copper / Copper Tripeptide-1 |
| Peptide Sequence | Gly-His-Lys (Cu²⁺) |
| Amino Acids | 3 (Tripeptide) |
| Metal Complex | Copper(II) — Cu²⁺ |
| Molecular Formula | C₁₄H₂₄CuN₆O₄ |
| Molecular Weight | 340.93 g/mol |
| PubChem CID | 73587 |
| Format | Lyophilized topical powder |
| Appearance | Blue-green powder |
| Purity | ≥99% (HPLC verified) |
| Storage | -20°C; protect from light and moisture |
| CAS Number | 49557-75-7 |
| Synonyms | Copper Tripeptide-1, Cu-GHK, Prezatide Copper |
Why Research Laboratories Select GHK-Cu Topical Powder
The topical powder format of GHK-Cu is specifically suited for laboratories investigating dermal penetration dynamics, formulation stability, and skin biology research models. Supplied in a larger powder quantity than the standard vial format, it allows researchers to prepare custom concentrations, test various delivery systems, and conduct repeated formulation experiments without the volume constraints of smaller reconstitutable vials.
- High-fill powder format — ideal for formulation development and dermal penetration research
- Same CAS 49557-75-7 compound as standard GHK-Cu — Gly-His-Lys copper(II) complex
- Allows custom concentration preparation for dermal model research studies
- Studied in laboratory skin biology models examining extracellular matrix signaling and cellular response
- Blue-green powder appearance confirms copper(II) complexation — visually distinct from non-copper peptides
- Referenced in preclinical research on fibroblast activity, collagen-associated signaling, and gene expression modulation
- Batch and lot identifiers on all labeling for full laboratory documentation compliance
Research Background
GHK-Cu was first identified in human plasma in 1973 by Loren Pickart, Ph.D. The copper-peptide complex has been referenced extensively in scientific literature on extracellular matrix biology, gene expression modulation, and cellular signaling. Preclinical studies have examined its role in fibroblast and keratinocyte response models, collagen-associated gene expression, and transcriptional regulation across a broad range of human genes. The topical powder format is referenced specifically in formulation research literature examining dermal penetration dynamics and skin biology models. All information provided here is for educational and reference purposes only and does not constitute medical or clinical guidance.
Reference sources: PubChem — GHK-Cu (CID 73587) | Wikipedia — Copper Peptide GHK-Cu
Shipping & Fulfillment
- Ships from U.S. warehouses — Florida, North Carolina, and California
- Overnight and 2-day shipping available at checkout
- Same-day processing on orders placed before 3:30 PM ET
- Discreet packaging with full tracking provided
- Bulk research orders welcome — contact us for volume pricing
Storage & Handling
- Store powder at -20°C away from light and moisture
- Keep container tightly sealed when not in use
- Handle using appropriate laboratory safety protocols for copper-peptide complexes
- Avoid moisture exposure — reseal immediately after each use
- Use appropriate personal protective equipment when handling powder form
Frequently Asked Questions
What is GHK-Cu Topical Powder?
GHK-Cu Topical Powder is the same Gly-His-Lys copper(II) complex as standard GHK-Cu (CAS 49557-75-7), supplied in a higher-fill powder format suited for formulation research and dermal penetration studies in laboratory settings. Supplied strictly for scientific, analytical, and in-vitro laboratory research use only.
How does the topical powder differ from the standard GHK-Cu vial?
The standard GHK-Cu vial is supplied in a smaller lyophilized format suited for reconstitution and in-vitro experiments. The topical powder is supplied in larger quantities suited for formulation development research, dermal penetration studies, and experiments requiring custom concentration preparation across multiple samples.
Is this the same compound as standard GHK-Cu?
Yes. Both products share the same CAS number (49557-75-7), molecular formula, and copper-peptide complex structure. The difference is the format and fill quantity, not the compound itself.
What purity is your GHK-Cu Topical Powder?
Every batch is independently verified to ≥99% HPLC purity. A Certificate of Analysis is available for each lot.
How fast does Nextday Peptides ship?
We ship from U.S. warehouses in Florida, North Carolina, and California. Overnight and 2-day shipping options are available. Orders placed before 3:30 PM ET are processed same day.
Are bulk orders available?
Yes. We accommodate bulk research orders. Contact us directly for volume pricing and availability.
Is this product approved for medical or cosmetic use?
No. This product is for laboratory research use only. It is not approved for human or veterinary use, and is not intended for diagnostic, therapeutic, cosmetic, or clinical applications.
What other compounds does Nextday Peptides carry?
We also carry standard GHK-Cu vials, BPC-157, TB-500, and MOTS-C. View our full research compounds catalog.
For Research Use Only — Not for human or veterinary consumption • Not evaluated by the FDA • Supplied by Nextday Peptides for laboratory research applications only
