Gonadorelin
Lyophilized powder • ≥99% HPLC Purity • Ships from U.S. Facilities • Research Use Only
Gonadorelin (GnRH, LHRH, CAS 33515-09-2) is a synthetic decapeptide with the sequence pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH₂ — identical in structure to endogenous gonadotropin-releasing hormone produced by hypothalamic neurons — supplied by Nextday Peptides in free base lyophilized format for laboratory and analytical research applications. As the primary hypothalamic regulator of the pituitary-gonadal axis, Gonadorelin activates GnRH receptors (GnRHR) on anterior pituitary gonadotroph cells via Gq/11-mediated phospholipase C signaling, making it an essential reference compound for laboratories investigating HPG axis biology, GnRHR pharmacology, gonadotropin signaling cascades, and pulsatile endocrine feedback dynamics. Each vial is independently verified to ≥99% HPLC purity with a Certificate of Analysis available on request. For scientific research use only.
Compound Specifications
| Compound Name | Gonadorelin / GnRH / LHRH / Gonadotropin-Releasing Hormone |
|---|---|
| Amino Acids | 10 (Decapeptide) — N-terminal pyroglutamate, C-terminal amide |
| Receptor Target | GnRHR (GnRH Receptor) — class A GPCR on pituitary gonadotrophs |
| Molecular Formula | C₅₅H₇₅N₁₇O₁₃ |
| Molecular Weight | 1,182.31 g/mol |
| CAS Number | 33515-09-2 (free base) |
| Form | Lyophilized powder |
| Appearance | White to off-white powder |
| Purity | ≥99% (HPLC verified) |
| Storage | -20°C lyophilized; 2–8°C after reconstitution (use within 14 days) |
| Peptide Sequence | pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH₂ |
| Salt Form | Free base (no acetate) |
| Intended Use | Laboratory / analytical / scientific research only |
Research Background
In controlled laboratory settings, investigators study Gonadorelin as a defined research material with characterized identity specifications suitable for analytical workflows. Reported sequence length in literature and product documentation: 10 (Decapeptide) — N-terminal pyroglutamate, C-terminal amide amino acids. Documented experimental target class: GnRHR (GnRH Receptor) — class A GPCR on pituitary gonadotrophs. Common research synonyms / identifiers: Gonadorelin / GnRH / LHRH / Gonadotropin-Releasing Hormone. Published literature and institutional protocols should be consulted by qualified personnel. Nextday Peptides does not provide experimental protocols for human use.
Storage & Handling
-20°C lyophilized; 2–8°C after reconstitution (use within 14 days)
- Use appropriate PPE and laboratory safe-handling practices.
- Reconstitute only with solvents suitable for your research method (e.g., sterile water, bacteriostatic water, or other protocol-defined vehicles).
- Do not use if packaging is compromised; contact support for lot documentation questions.
- Dispose of materials according to institutional chemical waste rules.
Shipping & Fulfillment
Orders are processed from U.S. facilities. Most in-stock research materials ship within 1–2 business days. Overnight options may be available where eligibility and destination allow. Packaging is selected to protect laboratory materials during transit.
Research Use Only
All products offered by Nextday Peptides are intended strictly for laboratory, analytical, and scientific research use only. They are not for human or veterinary consumption, clinical use, diagnostic use, or household use. Nothing on this page is medical advice. Resale for unlicensed or non-research purposes is prohibited. By purchasing, the buyer confirms they are a qualified research end-user and will handle materials in accordance with applicable laws and laboratory safety practices.
Frequently Asked Questions
Is Gonadorelin for human use?
No. This material is sold strictly for laboratory and scientific research. It is not a drug, supplement, or cosmetic, and is not for human or animal consumption.
Do you provide a Certificate of Analysis?
Yes. Lot-specific Certificates of Analysis (including HPLC purity where applicable) are available upon request for research documentation.
How should laboratories store this material?
Follow the storage guidance in the product specifications and your institutional SOPs. Lyophilized peptides are typically stored frozen, protected from light and moisture.
Who may purchase research materials?
Purchasers should be qualified research end-users who will use materials only in compliant laboratory contexts. Nextday Peptides reserves the right to refuse orders that fall outside research use.
Gonadorelin: laboratory research overview
Gonadorelin is supplied by Nextday Peptides as research-grade material for controlled laboratory, analytical, and scientific applications. Intended strictly for research use only — not for human or veterinary use. Certificate of Analysis (COA) available for laboratory intake records.
This material is also located under related phrasing such as Gonadorelin peptide, alongside Gonadorelin.
Labeled for procurement and inventory alignment with literature nomenclature. No consumer, clinical, dosage, or therapeutic framing. Ships from U.S. facilities to qualified research buyers.
Related research terminology for this listing
- Gonadorelin — laboratory identification and literature alignment
- Gonadorelin peptide — laboratory identification and literature alignment
Research use only. Not for human consumption, clinical administration, diagnostic use, or veterinary use. No outcome or dosing claims are implied.
