Snap-8

SNAP-8 Research Peptide (Acetyl Octapeptide-3)
Lyophilized Format • ≥99% HPLC Purity • Ships in 1–2 Business Days • U.S. Warehouses

SNAP-8 (Acetyl Octapeptide-3, CAS 868844-74-0) is a synthetic N-terminally acetylated and C-terminally amidated octapeptide with the sequence Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH₂, supplied by Nextday Peptides in lyophilized format for laboratory and analytical research applications. Developed as a structurally extended analog of acetyl hexapeptide-3, SNAP-8 was designed to mimic a segment of SNAP-25 — a key component of the SNARE protein complex involved in vesicle fusion and exocytosis — making it a useful research tool for in-vitro studies examining SNARE complex assembly, peptide-protein competitive binding dynamics, and neurotransmitter release pathway modeling. Each vial is independently verified to ≥99% HPLC purity with a Certificate of Analysis available on request. For scientific research use only.

Compound Specifications

Why Research Laboratories Select SNAP-8

SNAP-8 is one of the most widely studied synthetic SNAP-25 mimetic peptides in current SNARE complex biology research. As an eight amino acid synthetic analog designed to compete with the N-terminal fragment of endogenous SNAP-25 for SNARE complex binding sites, it provides a useful in-vitro tool for laboratories investigating vesicle fusion mechanisms, SNARE protein complex assembly dynamics, and competitive peptide-protein binding interactions in neurotransmission research models.

• Synthetic SNAP-25 mimetic octapeptide — designed to compete with the N-terminal fragment of SNAP-25 at SNARE complex binding sites
• N-acetylated and C-amidated — terminal modifications enhance peptide stability in experimental systems
• Structurally extended analog of acetyl hexapeptide-3 — two additional C-terminal residues (Ala-Asp) extend SNAP-25 sequence coverage
• Water soluble — easily prepared as aqueous research solutions for cell-based and in-vitro assay systems
• Studied in in-vitro SNARE complex assembly assays, vesicle fusion models, and competitive binding research
• Referenced in peer-reviewed literature on SNARE biology and peptide-protein interaction research
• Lyophilized format ensures stability and reproducibility across experimental runs
• Batch and lot identifiers on all labeling for full laboratory documentation compliance

Research Background

SNAP-8 was originally developed by Lipotec SA in Barcelona, Spain as a structural extension of acetyl hexapeptide-3 (Argireline). The SNARE complex — comprising syntaxin, SNAP-25, and synaptobrevin — is a fundamental molecular machinery for vesicle fusion and neurotransmitter exocytosis studied extensively in cell biology and neuroscience research. SNAP-8 has been referenced in peer-reviewed literature on SNARE complex competitive binding dynamics and peptide-protein interaction modeling. All information provided here is for educational and reference purposes only and does not constitute medical, clinical, or cosmetic guidance of any kind.

Reference sources: PubChem — Acetyl Octapeptide-3 | NIH PMC — SNARE Complex Peptide Research

Shipping & Fulfillment

• Ships from U.S. warehouses — Florida, North Carolina, and California
• Overnight and 2-day shipping available at checkout
• Same-day processing on orders placed before 3:30 PM ET
• Discreet packaging with full tracking provided
• Bulk research orders welcome — contact us for volume pricing

Storage & Handling

• Store lyophilized peptide at -20°C away from light and moisture
• After reconstitution store at 2–8°C and use promptly
• Avoid repeated freeze-thaw cycles to maintain integrity
• Handle using appropriate laboratory safety protocols
• Keep containers sealed when not in use

Frequently Asked Questions

For Research Use Only — Not for human or veterinary consumption • Not evaluated by the FDA • Not for cosmetic application • Supplied by Nextday Peptides for in-vitro laboratory research use only