B12 Cyanocobalamin

B12 Cyanocobalamin Research Compound
1mg/mL Sterile Solution • 10mL Vial • Ships in 1–2 Business Days • U.S. Warehouses

B12 Cyanocobalamin (CAS 68-19-9) is a synthetic form of Vitamin B12 — a water-soluble cobalt-containing corrinoid compound and essential cofactor in one-carbon metabolism — supplied by Nextday Peptides as a ready-to-use 1mg/mL sterile aqueous solution in a 10mL vial for laboratory and analytical research applications. As the most stable and widely used synthetic B12 form in laboratory research, Cyanocobalamin is a fundamental reference compound for laboratories investigating methionine synthase activity, homocysteine remethylation, DNA synthesis pathways, and mitochondrial energy metabolism. The characteristic deep red color is derived from the cobalt-cyanide coordination complex. Each batch is quality tested with a Certificate of Analysis available on request. For scientific research use only.

Compound Specifications

Why Research Laboratories Select B12 Cyanocobalamin

Cyanocobalamin is the most chemically stable synthetic form of Vitamin B12, making it the standard reference compound for B12-dependent pathway research in laboratory settings. As an essential cofactor for two critical enzymes — methionine synthase and methylmalonyl-CoA mutase — it sits at the intersection of one-carbon metabolism, DNA synthesis, and mitochondrial energy production research. Its deep red color and distinctive cobalt-corrinoid structure make it immediately identifiable in solution and easy to track in laboratory assays.

• Most stable synthetic B12 form — preferred over methylcobalamin and hydroxocobalamin for laboratory storage and handling
• Essential cofactor for methionine synthase — studied in homocysteine remethylation and SAMe production research
• Essential cofactor for methylmalonyl-CoA mutase — studied in mitochondrial energy metabolism and propionate pathway research
• Central to one-carbon metabolism — studied alongside folate, methionine, and choline in methylation pathway research
• Referenced in LipoC formulation research — active B12 component of lipotropic compound blends
• Ready-to-use 1mg/mL sterile solution — no reconstitution required
• Batch and lot identifiers on all labeling for full laboratory documentation compliance

Research Background

Vitamin B12 was first isolated in 1948 simultaneously by Rickes et al. at Merck and Smith et al. at Glaxo. Its crystal structure was determined by Dorothy Hodgkin in 1956 — work for which she received the Nobel Prize in Chemistry in 1964. Cyanocobalamin has been extensively studied as a cofactor in methionine synthase activity, homocysteine metabolism, and DNA synthesis research. Its role in methylmalonyl-CoA mutase activity makes it a key reference compound for mitochondrial energy pathway research. All information provided here is for educational and reference purposes only and does not constitute medical or clinical guidance.

Reference sources: PubChem — Cyanocobalamin (CID 16212801) | Sigma-Aldrich — Cyanocobalamin

Shipping & Fulfillment

• Ships from U.S. warehouses — Florida, North Carolina, and California
• Overnight and 2-day shipping available at checkout
• Same-day processing on orders placed before 3:30 PM ET
• Discreet packaging with full tracking provided
• Bulk research orders welcome — contact us for volume pricing

Storage & Handling

• Store at 2–8°C away from light — cyanocobalamin is photosensitive and degrades on prolonged light exposure
• Keep vial in original packaging or wrapped in foil when not in use
• Do not freeze — freezing may cause precipitation
• Keep vial tightly sealed when not in use
• Handle using appropriate laboratory safety protocols

Frequently Asked Questions

For Research Use Only — Not for human or veterinary consumption • Not evaluated by the FDA • Supplied by Nextday Peptides for laboratory research applications only