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How to Read a Certificate of Analysis (COA) for Research Peptides

How to Read a Certificate of Analysis (COA) for Research Peptides

A Certificate of Analysis (COA) is essential documentation accompanying research peptides. It verifies purity, identity, and batch tracking information used in laboratory environments.

Key Sections of a COA

1. Product Identification

  • Peptide name
  • CAS number (if applicable)
  • Sequence or formula
  • Batch (lot) number

2. Purity Data

COAs commonly include:

  • HPLC purity percentage
  • Chromatogram peaks
  • Total impurity calculations

Most laboratory-grade peptides fall within the ≥98–99% purity range.

3. Mass Spectrometry (MS) Confirmation

MS analysis confirms the molecular weight of the peptide, ensuring correct synthesis.

4. Appearance & Physical Checks

  • Lyophilized powder color
  • Moisture content
  • Form consistency

5. Storage Recommendations

Typically included to preserve molecular integrity.

Why COA–Batch Matching Matters

Researchers rely on batch-matched COAs to verify that the material used in experiments corresponds exactly to the documentation.

Nextday Sciences ensures COAs are:

  • Batch-aligned
  • Accurately labeled
  • Provided with each product
  • Clear and easy to read

Final Thoughts

Understanding a COA helps laboratories maintain accuracy, documentation integrity, and reliable experimental workflows.


Disclaimer: All products referenced are for laboratory research use only. Not for human or veterinary use.



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